KG-501 (2-naphthol-AS-E-phosphate)
$300.00
CAS No.: 18228-17-6
Catalog No.: 193713
Purity: 95%
MF: C17H13ClNO5P
MW: 377.72
Storage: 2-8 degree Celsius
SMILES: P(=O)(OC1=CC2=CC=CC=C2C=C1C(NC1=CC=C(C=C1)Cl)=O)(O)O
Catalog No.: 193713
Purity: 95%
MF: C17H13ClNO5P
MW: 377.72
Storage: 2-8 degree Celsius
SMILES: P(=O)(OC1=CC2=CC=CC=C2C=C1C(NC1=CC=C(C=C1)Cl)=O)(O)O
KG-501 (2-naphthol-AS-E-phosphate); 3-((4-chlorophenyl)carbamoyl)naphthalen-2-yl dihydrogen phosphate; CAS No.: 18228-17-6; KG-501 (2-naphthol-AS-E-phosphate). PROPERTIES: KG-501 (2-naphthol-AS-E-phosphate) is a crystalline compound with the molecular formula C17H12O5P. It exhibits good solubility in water and polar organic solvents. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety considerations include using gloves to prevent skin absorption and avoiding eye contact. With a molecular weight of approximately 339.25 g/mol, it demonstrates favorable absorption characteristics and moderate metabolic stability. The compound contains a phosphoric acid ester group contributing to its chemical reactivity and biological activity. Its logP value around 1.5 indicates a balance between hydrophilic and lipophilic properties. APPLICATIONS: KG-501 serves as a substrate for alkaline phosphatase enzyme, investigated in biochemistry research and diagnostic applications. In enzymology, it is used to study alkaline phosphatase activity and to develop colorimetric assays for enzyme measurement. The compound is employed in histochemical staining to visualize alkaline phosphatase expression in tissues and cells. Additionally, it functions as a research tool in molecular biology to investigate enzyme kinetics and in diagnostic kits for detecting alkaline phosphatase levels in clinical samples. According to "Enzyme Assays and Applications in Biochemistry," KG-501 provides a valuable substrate for studying alkaline phosphatase function and activity.
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