5-bromo-2-methyl-4-(trifluoromethyl)pyrimidine
$250.00
CAS No.: 1781830-29-2
Catalog No.: 192960
Purity: 95%
MF: C6H4BrF3N2
MW: 241.01
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC(=NC1)C)C(F)(F)F
Catalog No.: 192960
Purity: 95%
MF: C6H4BrF3N2
MW: 241.01
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC(=NC1)C)C(F)(F)F
5-bromo-2-methyl-4-(trifluoromethyl)pyrimidine; CAS No.: 1781830-29-2; 5-bromo-2-methyl-4-(trifluoromethyl)pyrimidine. PROPERTIES: This compound presents as a white to off-white crystalline solid with molecular formula C6H5BrF3N2 and a molecular weight of 235.01 g/mol. It exhibits a melting point in the range of 88-92 C and demonstrates moderate solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 5-bromo-2-methyl-4-(trifluoromethyl)pyrimidine may release toxic fumes upon heating. The bromo group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 5-bromo-2-methyl-4-(trifluoromethyl)pyrimidine serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its bromo substituent enables participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrimidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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