1-benzyl-4-methylpiperazine hydrochloride
$200.00
CAS No.: 374898-00-7
Catalog No.: 196286
Purity: 95%
MF: C12H19ClN2
MW: 226.751
Storage: 2-8 degree Celsius
SMILES: Cl.C(C1=CC=CC=C1)N1CCN(CC1)C
Catalog No.: 196286
Purity: 95%
MF: C12H19ClN2
MW: 226.751
Storage: 2-8 degree Celsius
SMILES: Cl.C(C1=CC=CC=C1)N1CCN(CC1)C
1-benzyl-4-methylpiperazine hydrochloride; CAS No.: 374898-00-7; 1-benzyl-4-methylpiperazine hydrochloride. PROPERTIES: This compound presents a 1-benzyl-4-methylpiperazine hydrochloride structure, combining a benzyl group, a methyl substituent, and a piperazine ring, and presented as a hydrochloride salt. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 207.3 g/mol (C12H18N2 {HCl). The melting point ranges between 150-155 C, and it exhibits good solubility in water and common organic solvents like ethanol and methanol. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 1-Benzyl-4-methylpiperazine hydrochloride serves as a specialized intermediate in pharmaceutical research. Its 1-benzyl-4-methylpiperazine hydrochloride structure enables diverse reactivity patterns, including nucleophilic substitution at the piperazine nitrogen and hydrogen bonding interactions through the benzyl group. In medicinal chemistry, it is used to develop bioactive molecules targeting G protein-coupled receptors and ion channels. The methyl substituent provides steric protection and metabolic stability. This compound also functions as a building block in the synthesis of bioactive peptides and depsipeptides. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the 1-benzyl-4-methylpiperazine hydrochloride scaffold for improved biological activity and pharmacokinetic properties.
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