4-chloro-1,2-dimethoxybenzene
$250.00
CAS No.: 16766-27-1
Catalog No.: 194051
Purity: 95%
MF: C8H9ClO2
MW: 172.611
Storage: 2-8 degree Celsius
SMILES: ClC1=CC(=C(C=C1)OC)OC
Catalog No.: 194051
Purity: 95%
MF: C8H9ClO2
MW: 172.611
Storage: 2-8 degree Celsius
SMILES: ClC1=CC(=C(C=C1)OC)OC
4-chloro-1,2-dimethoxybenzene; CAS No.: 16766-27-1; 4-chloro-1,2-dimethoxybenzene. PROPERTIES: 4-chloro-1,2-dimethoxybenzene is a colorless to pale yellow liquid with a molecular weight of 177.6 g/mol. It has a boiling point around 215-217 C at 760 mmHg and exhibits low water solubility while being miscible with common organic solvents such as dichloromethane, ethyl acetate, and tetrahydrofuran. The compound contains a chlorine substituent and two methoxy groups, which impart significant chemical stability and distinct reactivity patterns. Proper storage requires keeping the compound in a tightly sealed container at temperatures below 20 C, protected from light and moisture. Safety precautions include using protective gloves, eye protection, and ensuring adequate ventilation during handling. The compound may cause serious eye damage and skin irritation, and appropriate first aid measures should be followed in case of exposure. APPLICATIONS: 4-chloro-1,2-dimethoxybenzene serves as a versatile building block in organic synthesis, particularly in the preparation of various pharmaceuticals and specialty chemicals. Its unique substitution pattern makes it suitable for cross-coupling reactions, enabling the synthesis of complex aromatic systems for medicinal applications. In the field of medicinal chemistry, it functions as a precursor to certain antifungal and antibacterial agents, as documented in recent pharmaceutical research publications. The chlorine substituent provides a convenient handle for further functionalization, such as Suzuki-Miyaura couplings. Additionally, the compound is utilized in the production of liquid crystalline materials, where the methoxy groups contribute to desired physical properties. In materials science, it serves as a building block for certain types of conductive polymers and sensors, as reported in recent advances in organic materials science.
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