4-bromo-N-tert-butylbenzenesulfonamide
$200.00
CAS No.: 93281-65-3
Catalog No.: 194050
Purity: 95%
MF: C10H14BrNO2S
MW: 292.198
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=C1)S(=O)(=O)NC(C)(C)C
Catalog No.: 194050
Purity: 95%
MF: C10H14BrNO2S
MW: 292.198
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=C1)S(=O)(=O)NC(C)(C)C
4-bromo-N-tert-butylbenzenesulfonamide; CAS No.: 93281-65-3; 4-bromo-N-tert-butylbenzenesulfonamide. PROPERTIES: 4-bromo-N-tert-butylbenzenesulfonamide is a crystalline solid with a molecular weight of 271.3 g/mol. It typically exhibits a melting point in the range of 102-105 C and limited water solubility, though it dissolves readily in organic solvents such as methanol, ethanol, and dichloromethane. The compound contains reactive functional groups including a sulfonamide group, bromine substituent, and tert-butyl group, which contribute to its chemical versatility. For optimal storage, it should be kept in a tightly sealed container at temperatures below 20 C, preferably under inert atmosphere to prevent potential degradation. Safety considerations include wearing appropriate protective clothing, gloves, and eye/face protection to minimize exposure risk. The compound may cause eye irritation and skin irritation, and in case of accidental ingestion, immediate medical attention is advised. APPLICATIONS: 4-bromo-N-tert-butylbenzenesulfonamide serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and analgesic agents. Its unique substitution pattern allows for selective derivatization, making it suitable for constructing bioactive scaffolds, as reported in medicinal chemistry literature. In materials science, the compound functions as a building block for certain types of liquid crystalline materials and conductive polymers. The presence of the sulfonamide group imparts specific hydrogen bonding capabilities, influencing material properties. Additionally, it is utilized in the preparation of specialty dyes and pigments, where its structure contributes to desired solubility and stability characteristics. Through chemical modification of the sulfonamide group, it can be converted into various functionalized derivatives, expanding its application scope in organic synthesis. The bromine substituent provides a convenient handle for further functionalization, such as in cross-coupling reactions.
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