3,4-difluoro-5-methylbenzonitrile
$300.00
CAS No.: 1803833-51-3
Catalog No.: 193952
Purity: 95%
MF: C8H5F2N
MW: 153.131
Storage: 2-8 degree Celsius
SMILES: FC=1C=C(C#N)C=C(C1F)C
Catalog No.: 193952
Purity: 95%
MF: C8H5F2N
MW: 153.131
Storage: 2-8 degree Celsius
SMILES: FC=1C=C(C#N)C=C(C1F)C
3,4-difluoro-5-methylbenzonitrile; CAS No.: 1803833-51-3;3,4-difluoro-5-methylbenzonitrile. PROPERTIES: 3,4-difluoro-5-methylbenzonitrile is a fluorinated and methylated aromatic nitrile with molecular formula C8H5F2NO. It typically exists as a colorless liquid with a boiling point around 135-140 C. The compound has limited water solubility but dissolves well in organic solvents like dichloromethane or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic nitrogen-containing fumes. Proper storage involves keeping it in tightly sealed containers below 20 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic molecules. The difluoro substitution provides electron-withdrawing effects that enhance reactivity, while the methyl group offers steric protection (The Journal of Organic Chemistry). In pharmaceutical development, 3,4-difluoro-5-methylbenzonitrile contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).
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