(S)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride
$275.00
CAS No.: 1190890-11-9
Catalog No.: 192984
Purity: 95%
MF: C10H21ClN2O2
MW: 236.743
Storage: 2-8 degree Celsius
SMILES: Cl.NC[C@H]1N(CCC1)C(=O)OC(C)(C)C
Catalog No.: 192984
Purity: 95%
MF: C10H21ClN2O2
MW: 236.743
Storage: 2-8 degree Celsius
SMILES: Cl.NC[C@H]1N(CCC1)C(=O)OC(C)(C)C
(S)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride; CAS No.: 1190890-11-9; (S)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C10H18N2O2 {HCl and a molecular weight of 222.72 g/mol. It exhibits a melting point in the range of 142-146 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (S)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride may cause skin irritation. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (S)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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