(R)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride
$250.00
CAS No.: 1190890-12-0
Catalog No.: 192985
Purity: 95%
MF: C10H21ClN2O2
MW: 236.743
Storage: 2-8 degree Celsius
SMILES: Cl.NC[C@@H]1N(CCC1)C(=O)OC(C)(C)C
Catalog No.: 192985
Purity: 95%
MF: C10H21ClN2O2
MW: 236.743
Storage: 2-8 degree Celsius
SMILES: Cl.NC[C@@H]1N(CCC1)C(=O)OC(C)(C)C
(R)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride; CAS No.: 1190890-12-0; (R)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C10H18N2O2 {HCl and a molecular weight of 222.72 g/mol. It demonstrates a melting point in the range of 148-152 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (R)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride may cause skin irritation. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, (R)-tert-Butyl 2-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrrolidine derivatives. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrrolidine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
Reviews
Write Your Own Review