Cy7 Carboxylic acids
$500.00
CAS No.: 1628790-40-8
Catalog No.: WLZ0697
Purity: 95%
MF: C37H45ClN2O2
MW: 585.232
Storage: 2-8 degree Celsius
SMILES: [Cl-].C(=O)(O)CCCCCN1C(C(C2=CC=CC=C12)(C)C)=CC=C1C=C(CCC1)C=CC1=[N+](C2=CC=CC=C2C1(C)C)C
Catalog No.: WLZ0697
Purity: 95%
MF: C37H45ClN2O2
MW: 585.232
Storage: 2-8 degree Celsius
SMILES: [Cl-].C(=O)(O)CCCCCN1C(C(C2=CC=CC=C12)(C)C)=CC=C1C=C(CCC1)C=CC1=[N+](C2=CC=CC=C2C1(C)C)C
CAS No.: 1628790-40-8; Cy7 Carboxylic acids. PROPERTIES: Cy7 carboxylic acids are near-infrared fluorescent dyes with molecular weight approximately 700-800 g/mol depending on specific isomer. These dark purple solids exhibit absorption maxima around 750 nm and emission near 770 nm. They require storage at -20 C in foil-wrapped screw-cap vials to prevent photodegradation. Solubility in aqueous buffers is typically low (<0.1 mg/mL) without surfactants. Safety precautions involve using full-face shields during handling due to potential eye hazards, with engineering controls recommended for large-scale operations. APPLICATIONS: Cy7 carboxylic acids are predominantly utilized in medical imaging, particularly for lymphatic mapping and tumor detection during surgery. In clinical oncology, they enable real-time visualization of sentinel lymph nodes, as described in Journal of the American College of Surgeons surgical trials. For deep tissue imaging, their near-infrared emission penetrates biological tissues more effectively than visible dyes, with Theranostics preclinical studies demonstrating applications in orthotopic tumor models. In cardiovascular research, Cy7 derivatives track plaque progression in atherosclerosis models, as reported in Circulation Research imaging reports. Additionally, the dyes serve as fluorescent labels in multiplexed imaging platforms, with Nature Protocols publications outlining methods for simultaneous detection of multiple biomarkers in complex tissue sections.
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