Cy3 azide
$600.00
CAS No.: 1167421-28-4
Catalog No.: WLZ0672
Purity: 95%
MF: C33H43ClN6O
MW: 575.201
Storage: 2-8 degree Celsius
SMILES: [Cl-].N(=[N+]=[N-])CCCNC(CCCCCN1\C(\C(C2=CC=CC=C12)(C)C)=C\C=C\C1=[N+](C2=CC=CC=C2C1(C)C)C)=O
Catalog No.: WLZ0672
Purity: 95%
MF: C33H43ClN6O
MW: 575.201
Storage: 2-8 degree Celsius
SMILES: [Cl-].N(=[N+]=[N-])CCCNC(CCCCCN1\C(\C(C2=CC=CC=C12)(C)C)=C\C=C\C1=[N+](C2=CC=CC=C2C1(C)C)C)=O
CAS No.: 1167421-28-4; Cy3 azide. PROPERTIES: Cy3 azide is a fluorescent dye derivative with molecular formula C28H23N6O3S2 and molar mass 567.6 g/mol. It appears as dark red solid with characteristic absorption at ~550 nm and emission at ~570 nm. The compound is sensitive to photobleaching, requiring storage in amber glass vials at 4 C under nitrogen atmosphere. Solubility is enhanced in polar aprotic solvents, achieving up to 10 mg/mL in DMF. Safety considerations include wearing acid-resistant gloves and eye protection due to its potential to cause eye damage and skin irritation. APPLICATIONS: Cy3 azide is extensively used in bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. In fluorescence imaging, it enables labeling of biomolecules such as antibodies and nucleic acids, with Analytical Chemistry methodologies describing its application in super-resolution microscopy. For proteomics research, Cy3 azide facilitates site-specific protein labeling, as reported in Nature Methods studies on protein-protein interaction mapping. In therapeutic development, the dye serves as a tracking agent for nanoparticle delivery systems, with Journal of Controlled Release publications demonstrating real-time monitoring of cellular uptake. Additionally, Cy3 azide is employed in developing fluorescence resonance energy transfer (FRET) assays, with Biochemical Journal articles detailing its role in monitoring enzymatic activities and conformational changes in biological macromolecules.
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