Shield-1
$200.00
CAS No.: 914805-33-7
Catalog No.: 194643
Purity: 95%
MF: C42H56N2O10
MW: 748.914
Storage: 2-8 degree Celsius
SMILES: COC=1C=C(C=C(C1OC)OC)[C@@H](C(=O)N1[C@@H](CCCC1)C(=O)O[C@H](CCC1=CC(=C(C=C1)OC)OC)C1=CC(=CC=C1)OCCN1CCOCC1)CC
Catalog No.: 194643
Purity: 95%
MF: C42H56N2O10
MW: 748.914
Storage: 2-8 degree Celsius
SMILES: COC=1C=C(C=C(C1OC)OC)[C@@H](C(=O)N1[C@@H](CCCC1)C(=O)O[C@H](CCC1=CC(=C(C=C1)OC)OC)C1=CC(=CC=C1)OCCN1CCOCC1)CC
Shield-1; (R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate; CAS No.: 914805-33-7;Shield-1. PROPERTIES: Shield-1 is a pale yellow viscous liquid with a molecular formula of C28H31F6N5O6Si and a molecular weight of 677.60 g/mol. It has limited aqueous solubility but dissolves in common organic solvents. Storage should be at -20 C in a sealed amber vial protected from light and moisture. When handling, chemical-resistant gloves and eye protection are recommended due to its potential to cause skin and eye irritation. APPLICATIONS: Shield-1 is a synthetic small molecule used in synthetic biology. It stabilizes specific protein conformations by binding to designed proteostasis systems, enabling conditional protein activation (source: Nature Chemical Biology). In cellular models, Shield-1 controls protein levels and activities, facilitating study of gene function and signaling pathways. The compound has been utilized in developing inducible protein degradation systems, offering a tool for exploring protein homeostasis and developing novel therapeutic strategies (source: Molecular Cell).
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