Shield-1

Shield-1

Desmorpholinyl Navitoclax-NH-Me

Desmorpholinyl Navitoclax-NH-Me

AZD-5582 TFA

$380.00
CAS No.: NA
Catalog No.: 195130
Purity: 95%
MF: C60H79F3N8O10
MW: 1129.332
Storage: 2-8 degree Celsius
SMILES: O=C([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)CCC1)N[C@@H]3[C@H](OCC#CC#CCO[C@@H]4C(NC([C@H]5N(C([C@H](C6CCCCC6)NC([C@@H](NC)C)=O)=O)CCC5)=O)C7=C(C=CC=C7)C4)CC8=C3C=CC=C8.O=C(O)C(F)(F)F
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195130
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AZD-5582 TFA; (S,S,2S,2'S)-N,N'-((1S,1'S,2R,2'R)-(hexa-2,4-diyne-1,6-diylbis(oxy))bis(2,3-dihydro-1H-indene-2,1-diyl))bis(1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamide) 2,2,2-trifluoroacetic acid; AZD-5582 TFA. PROPERTIES: AZD-5582 TFA is a trifluoroacetate salt form of a small molecule inhibitor. This compound typically appears as a white to off-white solid. It has moderate solubility in water and is soluble in DMSO. AZD-5582 TFA should be stored at -20 C in a tightly sealed container to maintain stability. It is sensitive to moisture and light. Safety considerations include potential eye and skin irritation, so protective equipment is recommended. APPLICATIONS: AZD-5582 TFA is a potent inhibitor of the deubiquitylating enzyme USP7, with applications in cancer research. It is used to study the role of protein homeostasis in tumor biology. In preclinical models, it demonstrates antiproliferative effects in various cancer cell lines. In pharmacology, AZD-5582 TFA serves as a tool to investigate ubiquitin-proteasome system pathways. These applications are described in oncology research papers and pharmaceutical science literature.

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