R-7128;Mericitabine
$250.00
CAS No.: 940908-79-2
Catalog No.: 193673
Purity: 95%
MF: C18H26FN3O6
MW: 399.419
Storage: 2-8 degree Celsius
SMILES: C(C(C)C)(=O)O[C@@H]1[C@H](O[C@H]([C@]1(C)F)N1C(N=C(C=C1)N)=O)COC(C(C)C)=O
Catalog No.: 193673
Purity: 95%
MF: C18H26FN3O6
MW: 399.419
Storage: 2-8 degree Celsius
SMILES: C(C(C)C)(=O)O[C@@H]1[C@H](O[C@H]([C@]1(C)F)N1C(N=C(C=C1)N)=O)COC(C(C)C)=O
R-7128;Mericitabine; (2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-2-((isobutyryloxy)methyl)-4-methyltetrahydrofuran-3-yl isobutyrate; CAS No.: 940908-79-2; R-7128;Mericitabine. PROPERTIES: R-7128;Mericitabine is a white crystalline powder with the molecular formula C9H13N3O3. It exhibits good solubility in water and polar organic solvents. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety considerations include using gloves to prevent skin absorption and avoiding eye contact. With a molecular weight of approximately 223.21 g/mol, it demonstrates favorable absorption characteristics and moderate metabolic stability. The compound is a nucleoside analog containing a cytosine base and a modified sugar moiety. Its logP value around 0.8 indicates a predominantly hydrophilic nature. APPLICATIONS: R-7128;Mericitabine serves as a cytidine analog investigated for the treatment of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. In clinical research, it is used to study viral replication inhibition and to develop novel antiviral therapies with improved safety profiles. The compound is employed in combination studies with other antivirals to enhance treatment efficacy and prevent viral resistance. Additionally, it functions as a research tool in virology to investigate viral polymerase inhibition and in drug discovery to explore nucleoside analog approaches to antiviral therapy. According to "Nucleoside and Nucleotide Analogs in Antiviral Therapy," R-7128;Mericitabine provides insights into the development of effective antiviral agents targeting RNA and DNA viruses.
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