5'-O-DMT-N2-ibu-dG
$400.00
CAS No.: 68892-41-1
Catalog No.: 198518
Purity: 95%
MF: C35H37N5O7
MW: 639.709
Storage: 2-8 degree Celsius
SMILES: C(C(C)C)(=O)NC=1NC(C=2N=CN([C@H]3C[C@H](O)[C@@H](COC(C4=CC=C(C=C4)OC)(C4=CC=C(C=C4)OC)C4=CC=CC=C4)O3)C2N1)=O
Catalog No.: 198518
Purity: 95%
MF: C35H37N5O7
MW: 639.709
Storage: 2-8 degree Celsius
SMILES: C(C(C)C)(=O)NC=1NC(C=2N=CN([C@H]3C[C@H](O)[C@@H](COC(C4=CC=C(C=C4)OC)(C4=CC=C(C=C4)OC)C4=CC=CC=C4)O3)C2N1)=O
CAS No.: 68892-41-1; 5'-O-DMT-N2-ibu-dG. PROPERTIES: Appears as a yellow-orange amorphous solid. Molecular weight approximately 650 g/mol. Soluble in anhydrous acetonitrile and dichloromethane. Requires storage at -20 C under inert atmosphere. Safety measures include using organic vapor cartridges and avoiding skin contact. May cause eye damage and respiratory sensitization. APPLICATIONS: Functions as a protected deoxyguanosine building block in oligonucleotide synthesis. The 5'-O-DMT-N2-ibu-dG structure incorporates a dimethoxytrityl protecting group and isobutyryl modification at the N2 position as detailed in nucleic acid chemistry protocols. In antisense therapeutic development, it serves as a component for synthesizing nuclease-resistant oligonucleotides according to recent pharmaceutical chemistry research. Additionally, this compound is applied in creating PNA oligomers with improved binding affinity for gene regulation applications as reported in chemical biology literature.
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