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(R)-benzyl 1-aminopropan-2-ylcarbamate
$200.00
CAS No.: 346669-50-9
Catalog No.: 193140
Purity: 95%
MF: C11H16N2O2
MW: 208.261
Storage: 2-8 degree Celsius
SMILES: NC[C@@H](C)NC(OCC1=CC=CC=C1)=O
Catalog No.: 193140
Purity: 95%
MF: C11H16N2O2
MW: 208.261
Storage: 2-8 degree Celsius
SMILES: NC[C@@H](C)NC(OCC1=CC=CC=C1)=O
(R)-benzyl 1-aminopropan-2-ylcarbamate; CAS No.: 346669-50-9 (R)-benzyl 1-aminopropan-2-ylcarbamate. PROPERTIES: (R)-benzyl 1-aminopropan-2-ylcarbamate is a colorless to pale yellow liquid with a molecular weight of 237.3 g/mol. It has a boiling point around 140-145 C at reduced pressure and a density of approximately 1.1 g/cm?. The compound exhibits typical carbamate reactivity and should be handled with care to prevent hydrolysis. When working with (R)-benzyl 1-aminopropan-2-ylcarbamate, protective equipment including gloves and eye protection should be worn. Storage should be in a tightly sealed container at temperatures below 10 C, preferably under an inert atmosphere to prevent degradation. The compound is sensitive to acidic and basic conditions, which may cause hydrolysis of the carbamate group. APPLICATIONS: The chiral structure of (R)-benzyl 1-aminopropan-2-ylcarbamate makes it valuable in asymmetric synthesis and peptide chemistry. Its carbamate functionality allows for controlled release of the amine group upon deprotection, as demonstrated in Organic Syntheses. Derivatives of this compound have been explored in the development of beta-blockers and other cardiovascular pharmaceuticals, as reported in the Journal of Medicinal Chemistry. The benzyl protection provides a convenient handle for further functionalization in synthetic sequences. Additionally, the compound can be utilized in the preparation of chiral catalysts and ligands for asymmetric catalysis, as highlighted in Advanced Synthesis & Catalysis. The combination of the benzyl and carbamate protections makes this compound particularly useful in solid-phase synthesis and the preparation of combinatorial libraries for drug discovery, as described in the Journal of Combinatorial Chemistry.
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