(R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate
$200.00
CAS No.: 400652-48-4
Catalog No.: 193141
Purity: 95%
MF: C17H20N2O2
MW: 284.359
Storage: 2-8 degree Celsius
SMILES: NC[C@@H](CC1=CC=CC=C1)NC(OCC1=CC=CC=C1)=O
Catalog No.: 193141
Purity: 95%
MF: C17H20N2O2
MW: 284.359
Storage: 2-8 degree Celsius
SMILES: NC[C@@H](CC1=CC=CC=C1)NC(OCC1=CC=CC=C1)=O
(R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate; CAS No.: 400652-48-4 (R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate. PROPERTIES: (R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate is a crystalline solid with a molecular weight of 303.4 g/mol. It has a melting point between 120-125 C and exhibits moderate solubility in ethyl acetate and methylene chloride. The compound exhibits typical carbamate reactivity and should be handled with care to prevent hydrolysis. When working with (R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate, protective equipment including gloves and eye protection should be worn. Storage should be in a tightly sealed container at temperatures below 10 C, preferably under an inert atmosphere to prevent degradation. The compound is sensitive to acidic and basic conditions, which may cause hydrolysis of the carbamate group. APPLICATIONS: The chiral structure and carbamate protection of (R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate make it valuable in asymmetric synthesis and peptide chemistry. Its amino functionality allows for formation of amide bonds and participation in peptide coupling reactions, as demonstrated in Organic Syntheses. Derivatives of this compound have been explored in the development of kinase inhibitors and other targeted therapeutics, as reported in the Journal of Medicinal Chemistry. The benzyl protection provides a convenient handle for further functionalization in synthetic sequences. Additionally, the compound can be utilized in the synthesis of molecular sensors and fluorescent probes, as described in Chemical Communications. The combination of the benzyl and carbamate protections makes this compound particularly useful in solid-phase synthesis and the preparation of combinatorial libraries for drug discovery, as highlighted in the Journal of Combinatorial Chemistry.
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