(R)-2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine
$500.00
CAS No.: 210095-55-9
Catalog No.: 192833
Purity: 95%
MF: C17H19ClN2O
MW: 302.805
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C=C1)[C@H](C1=NC=CC=C1)OC1CCNCC1
Catalog No.: 192833
Purity: 95%
MF: C17H19ClN2O
MW: 302.805
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C=C1)[C@H](C1=NC=CC=C1)OC1CCNCC1
(R)-2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine; CAS No.: 210095-55-9; (R)-2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine. PROPERTIES: This chlorophenyl- and piperidyl-substituted pyridine has molecular formula C21H20ClN2O. It appears as a pale yellow oil. The (R)-2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate but limited water solubility. Its boiling point ranges between 220-225 C at 760 mmHg, and it has a molecular weight of approximately 361.86 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong oxidizing agents and may form explosive peroxides upon prolonged exposure to air. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (R)-2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine serves as a valuable intermediate in the synthesis of serotonin receptor antagonists for psychiatric disorders where the pyridine ring provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The chlorophenyl and piperidyl groups enhance metabolic stability by preventing oxidative degradation. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The methoxy group can be further functionalized through etherification or esterification reactions to produce various derivatives for chemical research applications.
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