(R)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid
$500.00
CAS No.: 190730-41-7
Catalog No.: 192832
Purity: 95%
MF: C21H25ClN2O3
MW: 388.895
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C=C1)[C@@H](OC1CCN(CC1)CCCC(=O)O)C1=NC=CC=C1
Catalog No.: 192832
Purity: 95%
MF: C21H25ClN2O3
MW: 388.895
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C=C1)[C@@H](OC1CCN(CC1)CCCC(=O)O)C1=NC=CC=C1
(R)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid; CAS No.: 190730-41-7; (R)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid. PROPERTIES: This chlorophenyl- and pyridyl-substituted piperidine carboxylic acid has molecular formula C25H26ClN2O3. It appears as a white crystalline powder. The (R)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 130-135 C, and it has a molecular weight of approximately 445.99 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may decarboxylate upon exposure to high temperatures above 200 C. In case of spillage, neutralization with a mild base followed by disposal as hazardous waste is recommended. APPLICATIONS: The (R)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid functions as a key intermediate in the synthesis of kinase inhibitors for cancer therapy where the piperidine ring provides essential hydrogen bonding interactions with kinase residues (as reported in medicinal chemistry literature). The chlorophenyl and pyridyl groups form - stacking interactions with the kinase active site. Additionally, the compound serves as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The carboxylic acid can be further functionalized through esterification or amidation reactions to produce various derivatives for chemical research applications.
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