7-chloro-[1,2,4]triazolo[1,5-a]pyridine; CAS No.: 1427452-48-9; 7-chloro-[1,2,4]triazolo[1,5-a]pyridine. PROPERTIES: 7-chloro-[1,2,4]triazolo[1,5-a]pyridine is a crystalline solid. Its molecular formula is C6H4ClN4, and the molecular weight is approximately 157.57 g/mol. The compound has a melting point of approximately 120-122 C. It is moderately soluble in common organic solvents such as ethyl acetate and tetrahydrofuran, but is poorly soluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a triazolopyridine ring and a chloro group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 7-chloro-[1,2,4]triazolo[1,5-a]pyridine serves as a valuable intermediate. The chloro group provides a site for substitution or coupling reactions. The triazolopyridine ring offers unique electronic effects. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For instance, in the development of certain anticancer drugs, the structure of 7-chloro-[1,2,4]triazolo[1,5-a]pyridine can be modified to enhance the drug's ability to target cancer cells and improve its therapeutic index (as described in medicinal chemistry research articles). Additionally, in the field of materials science, it can be incorporated into the synthesis of functional materials such as organic semiconductors or photovoltaic materials, where its structure can influence the material's electronic and optical properties (as mentioned in materials chemistry research papers).