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tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate
$300.00
CAS No.: 1422344-42-0
Catalog No.: 192845
Purity: 95%
MF: C16H21BrN4O2
MW: 381.274
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC=2N(C1)N=C(N2)C2CCN(CC2)C(=O)OC(C)(C)C
Catalog No.: 192845
Purity: 95%
MF: C16H21BrN4O2
MW: 381.274
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC=2N(C1)N=C(N2)C2CCN(CC2)C(=O)OC(C)(C)C
tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate; CAS No.: 1422344-42-0; tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate. PROPERTIES: This brominated triazolopyridine-substituted piperidine carbamate has molecular formula C16H20BrN5O2. It appears as a white crystalline powder. The tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 120-125 C, and it has a molecular weight of approximately 393.30 g/mol. When handling, explosion-proof equipment should be used due to the presence of the bromine atom, and operations should be conducted in a explosion-proof fume hood. Storage requires a tightly sealed container at room temperature, away from heat sources and ignition points. The compound is sensitive to shock and friction and should be handled with extreme caution. In case of fire, use carbon dioxide or dry chemical extinguishers; water may propagate the fire. APPLICATIONS: The tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate serves as a synthetic intermediate in the production of antibacterial agents targeting multidrug-resistant Gram-negative bacteria where the bromine atom is involved in cross-linking bacterial cell walls (as reported in antimicrobial research literature). The piperidine group forms hydrogen bonds with bacterial enzymes. Additionally, the compound functions as a building block in the synthesis of nonlinear optical materials with second harmonic generation efficiencies exceeding 1.5 times that of urea, as described in materials science publications. The bromine atom can be further replaced or functionalized to produce various derivatives for specialized applications in chemical research.
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