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5-bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine
$300.00
CAS No.: 1159813-10-1
Catalog No.: 197679
Purity: 95%
MF: C7H6BrN3
MW: 212.05
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=CC=2N1N=C(N2)C
Catalog No.: 197679
Purity: 95%
MF: C7H6BrN3
MW: 212.05
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=CC=2N1N=C(N2)C
5-bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine; CAS No.: 1159813-10-1;5-bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine. PROPERTIES: 5-bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine is a halogenated heterocycle with a molecular weight of 219.07 g/mol. This off-white crystalline solid has a melting point between 135-138 C. The molecule features a triazolo[1,5-a]pyridine ring system with a bromo substituent at position 5 and a methyl group at position 2. It demonstrates moderate solubility in common organic solvents such as methanol and acetone but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the bromine substituent's potential to cause skin and respiratory irritation and the heterocycle's general toxicity. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a building block in the synthesis of agrochemicals and pharmaceuticals, where the brominated triazolopyridine structure provides essential binding affinity to target enzymes. In medicinal chemistry, it has been employed in developing antimicrobial agents targeting bacterial and fungal pathogens and has shown utility in creating herbicides with selective activity against grassy weeds. The triazolopyridine scaffold has also garnered interest in materials science for developing fluorescent probes, leveraging the electron-deficient triazole core to tune optical properties. These applications are documented in publications from the Journal of Medicinal Chemistry and the Journal of Fluorescence.
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