tert-butyl 4-bromothiazol-2-yl(methyl)carbamate
$300.00
CAS No.: 697299-87-9
Catalog No.: 196078
Purity: 95%
MF: C9H13BrN2O2S
MW: 293.186
Storage: 2-8 degree Celsius
SMILES: BrC=1N=C(SC1)N(C(OC(C)(C)C)=O)C
Catalog No.: 196078
Purity: 95%
MF: C9H13BrN2O2S
MW: 293.186
Storage: 2-8 degree Celsius
SMILES: BrC=1N=C(SC1)N(C(OC(C)(C)C)=O)C
tert-butyl 4-bromothiazol-2-yl(methyl)carbamate; CAS No.: 697299-87-9; tert-butyl 4-bromothiazol-2-yl(methyl)carbamate. PROPERTIES: tert-butyl 4-bromothiazol-2-yl(methyl)carbamate is a crystalline powder with a molecular weight of approximately 303.1 g/mol. It has a melting point between 100-105 C. The compound is moderately soluble in common organic solvents like ethyl acetate and tetrahydrofuran but is practically insoluble in water. The tert-butyl group provides steric protection to the carbamate linkage. For proper storage, keep in a tightly sealed container at room temperature away from heat and moisture. Safety: This compound may cause narcotic effects. In case of exposure to large quantities, provide rest and fresh air. Use explosion-proof ventilation and lighting if handling large quantities. In case of fire, use water spray, foam, dry chemical, or carbon dioxide. APPLICATIONS: In pharmaceutical research, tert-butyl 4-bromothiazol-2-yl(methyl)carbamate serves as a protected amino acid derivative. The Boc group protects the amine during synthetic manipulations, and the bromine substituent allows for cross-coupling reactions. In organic synthesis, it is used as a building block for creating -turn mimetics in peptide research. The thiazole ring provides structural constraints that mimic peptide backbone conformations. In materials science, derivatives of this compound are explored for creating molecular recognition elements. The combination of the thiazole ring and the carbamate group creates a scaffold that can selectively bind certain analytes. These applications are supported by research in medicinal chemistry journals and materials science publications.
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