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N-methylthiazol-2-amine; CAS No.: 6142-06-9; N-methylthiazol-2-amine. PROPERTIES: N-methylthiazol-2-amine is a crystalline solid with a molecular weight of approximately 117.2 g/mol. It has a melting point between 70-75 C. The compound is moderately soluble in organic solvents like methanol and dimethylformamide but has limited water solubility. The methyl group on the amine increases its basicity compared to the unsubstituted counterpart. The compound is sensitive to oxidation and should be stored under nitrogen atmosphere at 2-8 C. Safety: This compound may cause skin irritation and serious eye damage. In case of accidental ingestion, rinse mouth immediately and seek medical advice. Use personal protective equipment including safety glasses and laboratory coats. APPLICATIONS: In pharmaceutical research, N-methylthiazol-2-amine is used as a building block for creating antitubercular agents. The methyl substituent on the amine enhances receptor binding affinity. In organic synthesis, it serves as a starting material for creating heterocyclic compounds via condensation reactions. The thiazole ring provides a platform for introducing various substituents that modulate biological activity. In materials science, derivatives of this compound are explored for creating conductive polymers. The amine group can be protonated to enhance electrical conductivity. These applications are documented in medicinal chemistry journals and polymer science research articles.