thiazole-5-carbonitrile
$200.00
CAS No.: 25742-12-5
Catalog No.: 196079
Purity: 95%
MF: C4H2N2S
MW: 110.141
Storage: 2-8 degree Celsius
SMILES: S1C=NC=C1C#N
Catalog No.: 196079
Purity: 95%
MF: C4H2N2S
MW: 110.141
Storage: 2-8 degree Celsius
SMILES: S1C=NC=C1C#N
thiazole-5-carbonitrile; CAS No.: 25742-12-5; thiazole-5-carbonitrile. PROPERTIES: Thiazole-5-carbonitrile is a crystalline solid with a molecular weight of approximately 113.1 g/mol. It has a melting point between 75-80 C and a boiling point around 180-190 C at 760 mmHg. The compound is moderately soluble in polar organic solvents like dimethylformamide and acetonitrile but has limited water solubility. The nitrile group imparts significant dipole moment to the molecule. For proper storage, keep in a tightly sealed container at room temperature away from heat sources. Safety: This compound may cause skin corrosion and serious eye damage. In case of skin contact, immediately wash with plenty of water and remove contaminated clothing. Use only in well-ventilated areas and avoid contact with oxidizing agents. APPLICATIONS: In pharmaceutical research, thiazole-5-carbonitrile is used as a building block for creating antiviral agents. The nitrile group can be hydrolyzed to the corresponding carboxylic acid, which forms ester linkages with biological targets. In organic synthesis, it serves as a starting material for creating thiazole-based heterocycles. The nitrile group undergoes nucleophilic addition reactions to form more complex ring systems. In materials science, it is employed in creating electron-deficient materials for organic electronics. The nitrile group withdraws electron density from the thiazole ring, creating materials with specific electron transport properties. These applications are described in medicinal chemistry journals and materials science research articles.
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