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4-(thiazol-2-yl)benzaldehyde; CAS No.: 198904-53-9; 4-(thiazol-2-yl)benzaldehyde. PROPERTIES: 4-(thiazol-2-yl)benzaldehyde is a crystalline solid with a molecular weight of approximately 197.2 g/mol. It has a melting point in the range of 98-102 C and a boiling point around 290 C at 760 mmHg. The compound exhibits moderate solubility in common organic solvents such as dimethylformamide and tetrahydrofuran but is practically insoluble in water. Its UV spectrum shows characteristic absorption maxima around 280 nm. For proper storage, it should be kept in a cool, dry place away from strong oxidizing agents and light. Preferably stored at -20 C in a desiccator to prevent moisture-induced degradation. Safety: This compound may cause severe eye damage and skin irritation. In case of contact, rinse immediately with plenty of water and seek medical advice. Use under well-ventilated conditions and employ proper engineering controls to minimize exposure. APPLICATIONS: In pharmaceutical research, 4-(thiazol-2-yl)benzaldehyde serves as a key intermediate for synthesizing bioactive molecules. The conjugated system between the thiazole and benzaldehyde moieties makes it suitable for preparing Schiff bases, which have potential antiviral and anticancer activities. In organic chemistry, it undergoes various condensation reactions to form macrocyclic compounds. These macrocycles can coordinate with metal ions, finding applications in supramolecular chemistry. In the fragrance industry, derivatives of this compound are used to create novel aromatic compounds with unique olfactory profiles. The thiazole ring contributes to the stability of these fragrances. These applications are supported by research publications in organic synthesis and medicinal chemistry journals.