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2-chloro-6-fluoroquinoxaline; CAS No.: 55687-33-7; 2-chloro-6-fluoroquinoxaline. PROPERTIES: 2-chloro-6-fluoroquinoxaline is a crystalline solid with molecular formula C8H4ClFN2, having a molar mass of approximately 184.58 g/mol. It demonstrates low water solubility but good solubility in methylene chloride and acetone. Melting point determinations typically yield values between 85-89 C. Proper storage requires maintaining in well-sealed containers at temperatures below 20 C, protected from light and moisture. Safety considerations identify it as harmful if swallowed and causing skin irritation. Precautionary measures recommend using explosion-proof ventilation and providing eyewash stations in handling areas. APPLICATIONS: This compound serves as a valuable intermediate in the synthesis of antimalarial agents, particularly those targeting Plasmodium falciparum. Its chloro substituent at position 2 and fluoro group at position 6 enable selective alkylation reactions crucial for constructing target molecules. In agrochemical research (non-agricultural context), it contributes to safener compound development through controlled derivatization pathways. Additionally, the compound supports materials science applications in fluorinated polymer development for electronic devices, with methodologies published in Malaria Journal and chemical patent literature, illustrating its significance in antimalarial therapy and materials innovation.