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3-chloroquinoxaline-2-carboxylic acid; CAS No.: 20254-76-6; 3-chloroquinoxaline-2-carboxylic acid. PROPERTIES: 3-chloroquinoxaline-2-carboxylic acid presents as a white crystalline powder with molecular formula C8H4ClN2O2, possessing a molar mass of approximately 201.58 g/mol. It demonstrates limited water solubility but good solubility in hot methanol and DMSO. Melting point observations typically fall between 230-234 C. Proper storage requires maintaining in tightly sealed containers at room temperature, protected from light and moisture. Safety precautions highlight potential to cause serious eye damage and skin irritation. Proper handling involves using protective eyewear and gloves, with accidental release requiring containment with inert materials. APPLICATIONS: This compound functions as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting cancer-related signaling pathways. Its chloro substituent at position 3 and carboxylic acid at position 2 enable selective modification for constructing bioactive molecules. In medicinal chemistry research, it supports the development of antiviral agents through controlled derivatization pathways. The compound also contributes to materials science applications in fluorescent dye development for detecting biomolecules, with methodologies described in chemical literature and patent databases, demonstrating its cross-disciplinary utility in oncology and analytical chemistry tools.