6-fluoroquinoxalin-2(1H)-one
$200.00
CAS No.: 55687-23-5
Catalog No.: 196048
Purity: 95%
MF: C8H5FN2O
MW: 164.139
Storage: 2-8 degree Celsius
SMILES: FC=1C=C2N=CC(NC2=CC1)=O
Catalog No.: 196048
Purity: 95%
MF: C8H5FN2O
MW: 164.139
Storage: 2-8 degree Celsius
SMILES: FC=1C=C2N=CC(NC2=CC1)=O
6-fluoroquinoxalin-2(1H)-one; CAS No.: 55687-23-5; 6-fluoroquinoxalin-2(1H)-one. PROPERTIES: 6-fluoroquinoxalin-2(1H)-one appears as a white crystalline powder with molecular formula C8H4FN3O, possessing a molar mass of approximately 179.14 g/mol. It demonstrates limited water solubility but good solubility in methanol and dimethylformamide. Melting point observations typically fall between 170-174 C. Proper storage requires maintaining in tightly sealed containers at room temperature, protected from moisture and strong acids. Safety precautions highlight potential to cause skin irritation and serious eye damage. Proper handling involves using protective eyewear and gloves, with accidental release requiring containment with inert materials. APPLICATIONS: This compound functions as a key intermediate in the synthesis of anticancer agents, particularly those targeting poly(ADP-ribose) polymerase (PARP) enzymes. Its fluoro substituent at position 6 enables selective modification for constructing bioactive molecules. In medicinal chemistry research, it supports the development of kinase inhibitors through controlled derivatization pathways. The compound also contributes to materials science applications in fluorescent probe development for bioimaging, with methodologies described in Journal of Medicinal Chemistry and chemical supplier catalogs, demonstrating its cross-disciplinary utility in oncology and analytical chemistry tools.
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