8-bromoquinoline-5-carboxylic acid
$400.00
CAS No.: 204782-96-7
Catalog No.: 196032
Purity: 95%
MF: C10H6BrNO2
MW: 252.067
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=2C=CC=NC12)C(=O)O
Catalog No.: 196032
Purity: 95%
MF: C10H6BrNO2
MW: 252.067
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=2C=CC=NC12)C(=O)O
8-bromoquinoline-5-carboxylic acid; CAS No.: 204782-96-7; 8-bromoquinoline-5-carboxylic acid. PROPERTIES: 8-bromoquinoline-5-carboxylic acid is a crystalline compound with molecular formula C9H5BrNO2, having a molar mass of approximately 259.05 g/mol. It demonstrates limited water solubility but dissolves in hot methanol and dimethylformamide. Melting point determinations typically yield values between 230-234 C. Proper storage requires maintaining in well-sealed containers at room temperature, protected from light and moisture. Safety considerations identify it as harmful if swallowed and causing skin irritation. Precautionary measures recommend using protective equipment and implementing engineering controls to minimize dust generation. APPLICATIONS: This compound serves as a valuable intermediate in the synthesis of anticancer agents, particularly those targeting protein kinases. Its bromine substituent at position 8 and carboxylic acid at position 5 enable selective modification for constructing bioactive molecules. In medicinal chemistry research, it supports the development of antibacterial agents through controlled derivatization pathways. The compound also contributes to materials science applications in photodynamic therapy agents, with methodologies published in Journal of Medicinal Chemistry and related pharmaceutical patents, illustrating its significance in oncology and infectious disease therapeutic agent innovation.
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