methyl 8-bromoquinoline-5-carboxylate
$300.00
CAS No.: 253787-45-0
Catalog No.: 196033
Purity: 95%
MF: C11H8BrNO2
MW: 266.094
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=2C=CC=NC12)C(=O)OC
Catalog No.: 196033
Purity: 95%
MF: C11H8BrNO2
MW: 266.094
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=2C=CC=NC12)C(=O)OC
methyl 8-bromoquinoline-5-carboxylate; CAS No.: 253787-45-0; methyl 8-bromoquinoline-5-carboxylate. PROPERTIES: Methyl 8-bromoquinoline-5-carboxylate appears as a white crystalline solid with molecular formula C10H7BrNO2, possessing a molar mass of approximately 273.07 g/mol. It demonstrates limited water solubility but good solubility in methanol and ethyl acetate. Melting point observations typically fall between 85-89 C. Proper storage requires maintaining in tightly sealed containers at temperatures below 30 C, protected from light and moisture. Safety precautions highlight potential to cause skin irritation and serious eye damage. Proper handling involves using protective eyewear and gloves, with accidental release requiring containment with inert materials. APPLICATIONS: This compound functions as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting cancer-related signaling pathways. Its bromine substituent at position 8 and methyl ester at position 5 enable selective modification for constructing target molecules. In agrochemical research (non-agricultural application), it contributes to safener compound development through controlled hydrolysis reactions. Additionally, the compound supports materials science applications in fluorescent probe development for detecting biomolecules, with methodologies described in chemical literature and patent databases, demonstrating its cross-disciplinary utility in oncology and analytical chemistry tools.
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