5-fluoroquinolin-7-ol
$400.00
CAS No.: 1261771-12-3
Catalog No.: 192226
Purity: 95%
MF: C9H6FNO
MW: 163.151
Storage: 2-8 degree Celsius
SMILES: FC1=C2C=CC=NC2=CC(=C1)O
Catalog No.: 192226
Purity: 95%
MF: C9H6FNO
MW: 163.151
Storage: 2-8 degree Celsius
SMILES: FC1=C2C=CC=NC2=CC(=C1)O
5-fluoroquinolin-7-ol; CAS No.: 1261771-12-3; 5-fluoroquinolin-7-ol. PROPERTIES: 5-fluoroquinolin-7-ol appears as a white crystalline powder with molecular formula C9H5FNO2. It has a melting point of approximately 195-200 C and exhibits pH-dependent solubility with increased dissolution in basic solutions. Proper storage involves maintaining in a sealed container at 15-25 C with desiccant. Safety considerations include using corrosion-resistant equipment due to its weakly acidic nature and standard PPE to prevent skin contact. APPLICATIONS: This fluorinated quinoline derivative is employed in the development of antimalarial agents. The hydroxyl group at position 7 provides a site for PEGylation, enhancing the pharmacokinetic properties of the molecule as reported in tropical medicine research. In materials science, 5-fluoroquinolin-7-ol derivatives have found use in creating self-assembled monolayers for surface modification. According to materials chemistry journals, the quinoline core promotes adsorption onto metal surfaces while the fluorine substituent imparts chemical resistance.
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