7-chloroquinolin-5-ol
$400.00
CAS No.: 1236162-22-3
Catalog No.: 192228
Purity: 95%
MF: C9H6ClNO
MW: 179.606
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C=2C=CC=NC2C1)O
Catalog No.: 192228
Purity: 95%
MF: C9H6ClNO
MW: 179.606
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C=2C=CC=NC2C1)O
7-chloroquinolin-5-ol; CAS No.: 1236162-22-3; 7-chloroquinolin-5-ol. PROPERTIES: 7-chloroquinolin-5-ol is a crystalline powder with molecular formula C9H5ClNO2. It has a melting point around 195-200 C and shows pH-dependent solubility with increased dissolution in basic solutions. Proper storage involves maintaining in a sealed container at 15-25 C with desiccant. Safety considerations include using corrosion-resistant equipment due to its weakly acidic nature and standard PPE to prevent skin contact. APPLICATIONS: This chlorinated quinoline derivative is employed in the development of antimicrobial agents. The hydroxyl group at position 5 allows for glycosylation, creating fluoroquinolone antibiotics with enhanced antibacterial spectra as reported in pharmaceutical chemistry journals. In bioanalytical applications, 7-chloroquinolin-5-ol serves as a fluorescent probe for detecting specific metal ions. According to analytical chemistry research, the quinoline scaffold's fluorescence is quenched upon metal coordination, enabling sensitive detection methods with limits approaching nanomolar concentrations.
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