5,7-difluoroquinolin-3-ol
$400.00
CAS No.: 1483673-86-4
Catalog No.: 192388
Purity: 95%
MF: C9H5F2NO
MW: 181.141
Storage: -20 degree Celsius
SMILES: FC1=C2C=C(C=NC2=CC(=C1)F)O
Catalog No.: 192388
Purity: 95%
MF: C9H5F2NO
MW: 181.141
Storage: -20 degree Celsius
SMILES: FC1=C2C=C(C=NC2=CC(=C1)F)O
5,7-difluoroquinolin-3-ol; CAS No.: 1483673-86-4; 5,7-difluoroquinolin-3-ol. PROPERTIES: 5,7-difluoroquinolin-3-ol is a crystalline substance with molecular formula C9H5F2NO. It has a melting point of approximately 210-215 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This difluorinated quinoline alcohol is used in the development of anticancer prodrugs. The hydroxyl group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 5,7-difluoroquinolin-3-ol serves as a building block for creating photoaffinity labels. According to biochemical journals, the quinoline scaffold provides a fluorescent signal while the fluorine groups enable photoinduced cross-linking with target proteins.
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