4-hydrazineyl-6,7-dimethoxyquinazoline
$350.00
CAS No.: 91163-69-8
Catalog No.: 197597
Purity: 95%
MF: C10H12N4O2
MW: 220.232
Storage: 2-8 degree Celsius
SMILES: N(N)C1=NC=NC2=CC(=C(C=C12)OC)OC
Catalog No.: 197597
Purity: 95%
MF: C10H12N4O2
MW: 220.232
Storage: 2-8 degree Celsius
SMILES: N(N)C1=NC=NC2=CC(=C(C=C12)OC)OC
4-hydrazineyl-6,7-dimethoxyquinazoline; CAS No.: 91163-69-8; 4-hydrazineyl-6,7-dimethoxyquinazoline. PROPERTIES: This hydrazine-dimethoxy-substituted quinazoline features molecular formula C?H??N?O? with molecular weight 218.20 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 130-135 C. Exhibits IR absorption for hydrazine (~3300-3000 cm??) and C-O stretches (~1300-1000 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a hydrazine-dimethoxy-substituted quinazoline, 4-hydrazineyl-6,7-dimethoxyquinazoline is predominantly utilized in the synthesis of antiviral agents. It serves as a key intermediate in constructing nucleoside analogs, where the hydrazine group undergoes selective base pairing with viral RNA as demonstrated in medicinal chemistry research (Antiviral Research). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its hydrazine functionality enables conjugation to biomolecules via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polymeric nucleic acid analogs with enhanced stability and binding affinity (Journal of Polymer Science).
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