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6-amino-2-(methylthio)pyrimidin-4-ol; CAS No.: 1074-41-5; ChemShuttle offers 6-amino-2-(methylthio)pyrimidin-4-ol for antimetabolite therapies targeting dihydrofolate reductase. The methylthio group enhances membrane permeability compared to oxygen analogs, while the amino groups maintain target interactions. Our cell cycle analysis identifies S-phase arrest indicative of DNA synthesis inhibition.