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2-(methylthio)pyrimidine-4,6-diamine; CAS No.: 1005-39-6; ChemShuttle s 2-(methylthio)pyrimidine-4,6-diamine serves as a building block for antifolate agents. The thioether and amino groups mimic pteridine ring interactions in DHFR binding, while allowing structural modifications to overcome drug resistance. Our services include cytotoxicity screening across multidrug-resistant cell lines.