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5-bromo-2-methoxypyrimidin-4-amine; CAS No.: 148214-56-6; 5-bromo-2-methoxypyrimidin-4-amine. PROPERTIES: 5-bromo-2-methoxypyrimidin-4-amine has a molecular formula of C5H5BrN3O with molecular weight approximately 223.02 g/mol. It typically forms pale yellow crystals with a melting point around 152-155 C. The compound demonstrates moderate solubility in polar organic solvents and limited water solubility. Recommended storage conditions include maintaining in a tightly sealed container at room temperature away from direct sunlight and moisture. Safety considerations involve using a fume hood during handling to prevent inhalation of dust particles, which may cause respiratory irritation. In case of accidental ingestion, immediate medical consultation is advised. The amine functionality requires careful handling to avoid reaction with electrophilic substances. APPLICATIONS: 5-bromo-2-methoxypyrimidin-4-amine is utilized as a building block for antiparasitic and antiviral drug development. Its bromine substituent facilitates cross-coupling reactions, while the methoxy group provides steric and electronic effects beneficial for receptor binding. In agrochemical research (though non-agricultural uses are emphasized here), it has been employed in developing novel herbicide safeners, as mentioned in specialized agrochemical formulation literature. The compound also serves as a precursor for fluorescent probes used in bioimaging applications, with methodologies detailed in analytical chemistry journals focusing on heterocyclic fluorescent markers.