5-iodo-4-methoxypyrimidin-2-amine
$300.00
CAS No.: 89322-66-7
Catalog No.: 196444
Purity: 95%
MF: C5H6IN3O
MW: 251.027
Storage: 2-8 degree Celsius
SMILES: IC=1C(=NC(=NC1)N)OC
Catalog No.: 196444
Purity: 95%
MF: C5H6IN3O
MW: 251.027
Storage: 2-8 degree Celsius
SMILES: IC=1C(=NC(=NC1)N)OC
5-iodo-4-methoxypyrimidin-2-amine; CAS No.: 89322-66-7; 5-iodo-4-methoxypyrimidin-2-amine. PROPERTIES: 5-iodo-4-methoxypyrimidin-2-amine features molecular formula C5H5IN3O with molecular weight approximately 263.02 g/mol. It generally appears as a pale yellow solid with a melting point around 165-168 C. The compound exhibits limited solubility in water but dissolves in polar organic solvents like DMSO and DMF. Recommended storage involves keeping in a tightly sealed container at 2-8 C to prevent degradation. Safety precautions include using respiratory protection when handling powder forms to prevent inhalation, which may cause respiratory irritation. The iodine substituent may release toxic fumes when exposed to heat. In case of eye contact, immediate flushing with water for at least 15 minutes is advised. APPLICATIONS: 5-iodo-4-methoxypyrimidin-2-amine acts as a valuable intermediate in the development of radiopharmaceuticals. Its iodine substituent enables radiolabeling for imaging applications. In nuclear medicine research, it has been utilized to create novel agents for thyroid imaging, as described in radiopharmaceutical chemistry journals. The methoxy group provides steric effects beneficial for receptor binding. Additionally, this compound serves as a building block for cross-coupling reactions in organic synthesis, with applications reported in synthetic chemistry literature focusing on Suzuki-Miyaura couplings.
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