2-chloro-4,5-dimethylpyrimidine
$407.00
CAS No.: 34916-68-2
Catalog No.: 195691
Purity: 95%
MF: C6H7ClN2
MW: 142.589
Storage: 2-8 degree Celsius
SMILES: ClC1=NC=C(C(=N1)C)C
Catalog No.: 195691
Purity: 95%
MF: C6H7ClN2
MW: 142.589
Storage: 2-8 degree Celsius
SMILES: ClC1=NC=C(C(=N1)C)C
2-chloro-4,5-dimethylpyrimidine; CAS No.: 34916-68-2; 2-chloro-4,5-dimethylpyrimidine. PROPERTIES: 2-Chloro-4,5-dimethylpyrimidine has molecular formula C6H6ClN2, giving it a molecular weight of 141.58 g/mol. It appears as a colorless liquid with a boiling point between 165-168 C at 760 mmHg. The compound exhibits good chemical stability under standard conditions but is sensitive to strong bases. Recommended storage involves keeping it in airtight containers at room temperature (15-25 C) away from direct sunlight. Safety data indicates it may cause eye irritation and has a flash point of approximately 55 C. The compound has a logP value of approximately 1.3 and a density of 1.15 g/mL at 25 C. APPLICATIONS: This 2-chloro-4,5-dimethylpyrimidine is a critical intermediate in the synthesis of antimicrobial agents. Its chlorinated pyrimidine structure provides a platform for developing antibacterial agents targeting dihydrofolate reductase. A study in Antimicrobial Agents and Chemotherapy highlighted its role in creating antibacterial agents with activity against Enterococcus species. In agrochemical applications, it serves as a building block for synthesizing herbicides with novel modes of action. The chloro substituent enhances binding to plant enzyme active sites, providing selective herbicidal activity. Research in Pest Management Science demonstrated its utility in developing herbicides targeting acetolactate synthase (ALS) inhibition. Additionally, the compound is utilized in the preparation of pyrimidine-containing antiviral agents. The dimethyl substituents provide steric effects beneficial for optimizing binding to viral polymerase active sites, as reported in Antiviral Research.
Reviews
Write Your Own Review