4-chloro-2-(methylthio)-5-pyrimidinecarboxylic acid
$300.00
CAS No.: 74840-34-9
Catalog No.: 194919
Purity: 95%
MF: C6H5ClN2O2S
MW: 204.638
Storage: 2-8 degree Celsius
SMILES: ClC1=NC(=NC=C1C(=O)O)SC
Catalog No.: 194919
Purity: 95%
MF: C6H5ClN2O2S
MW: 204.638
Storage: 2-8 degree Celsius
SMILES: ClC1=NC(=NC=C1C(=O)O)SC
4-chloro-2-(methylthio)-5-pyrimidinecarboxylic acid; CAS No.: 74840-34-9; 4-chloro-2-(methylthio)-5-pyrimidinecarboxylic acid. PROPERTIES: 4-chloro-2-(methylthio)-5-pyrimidinecarboxylic acid is a crystalline solid. Its molecular formula is C7H5ClN2O2S, and the molecular weight is approximately 220.65 g/mol. The compound has a melting point of approximately 150-152 C. It is moderately soluble in common organic solvents such as methanol and ethyl acetate, but is poorly soluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a pyrimidine ring, a chloro group, a methylthio group, and a carboxylic acid group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 4-chloro-2-(methylthio)-5-pyrimidinecarboxylic acid serves as a versatile intermediate. The carboxylic acid group can undergo reactions such as esterification and amidation. The pyrimidine ring and chloro group provide unique electronic effects. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain antimicrobial agents, the structure of 4-chloro-2-(methylthio)-5-pyrimidinecarboxylic acid can be modified to enhance the drug's antimicrobial activity and selectivity (as described in medicinal chemistry research articles). Additionally, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in catalysis and sensing (as mentioned in organic chemistry research papers).
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