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methyl 6-fluoropyrazolo[1,5-a]pyridine-3-carboxylate
$225.00
CAS No.: 1802489-63-9
Catalog No.: 192901
Purity: 95%
MF: C9H7FN2O2
MW: 194.165
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC=2N(C1)N=CC2C(=O)OC
Catalog No.: 192901
Purity: 95%
MF: C9H7FN2O2
MW: 194.165
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC=2N(C1)N=CC2C(=O)OC
methyl 6-fluoropyrazolo[1,5-a]pyridine-3-carboxylate; CAS No.: 1802489-63-9; methyl 6-fluoropyrazolo[1,5-a]pyridine-3-carboxylate. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C9H7FN2O2 and a molecular weight of 196.16 g/mol. It exhibits a melting point in the range of 112-116 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as methyl 6-fluoropyrazolo[1,5-a]pyridine-3-carboxylate may cause skin irritation. The ester group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, methyl 6-fluoropyrazolo[1,5-a]pyridine-3-carboxylate serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its fluorine substituent enables improved metabolic stability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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