methyl 4-fluoropyrazolo[1,5-a]pyridine-3-carboxylate; CAS No.: 1802489-64-0; methyl 4-fluoropyrazolo[1,5-a]pyridine-3-carboxylate. PROPERTIES: This compound presents as a colorless to pale yellow crystalline solid with molecular formula C9H7FN2O2 and a molecular weight of 196.16 g/mol. It demonstrates a melting point in the range of 108-112 C and shows moderate solubility in common organic solvents like methanol and dichloromethane. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as methyl 4-fluoropyrazolo[1,5-a]pyridine-3-carboxylate may cause skin irritation. The ester group requires careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical industry, methyl 4-fluoropyrazolo[1,5-a]pyridine-3-carboxylate serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrazole derivatives. Its fluorine substituent enables improved metabolic stability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.