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methyl 2-((tert-butoxycarbonyl)amino)pyrazolo[1,5-a]pyridine-3-carboxylate
$400.00
CAS No.: 1476799-73-1
Catalog No.: 192900
Purity: 95%
MF: C14H17N3O4
MW: 291.307
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)NC1=NN2C(C=CC=C2)=C1C(=O)OC
Catalog No.: 192900
Purity: 95%
MF: C14H17N3O4
MW: 291.307
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)NC1=NN2C(C=CC=C2)=C1C(=O)OC
methyl 2-((tert-butoxycarbonyl)amino)pyrazolo[1,5-a]pyridine-3-carboxylate; CAS No.: 1476799-73-1; methyl 2-((tert-butoxycarbonyl)amino)pyrazolo[1,5-a]pyridine-3-carboxylate. PROPERTIES: This compound presents as a white crystalline solid with molecular formula C13H14N3O3 and a molecular weight of 268.26 g/mol. It demonstrates a melting point in the range of 128-132 C and shows moderate solubility in common organic solvents like ethyl acetate and tetrahydrofuran. The substance is sensitive to acidic hydrolysis and should be stored in neutral conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as methyl 2-((tert-butoxycarbonyl)amino)pyrazolo[1,5-a]pyridine-3-carboxylate may release irritating vapors upon heating. The tert-butoxycarbonyl group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, methyl 2-((tert-butoxycarbonyl)amino)pyrazolo[1,5-a]pyridine-3-carboxylate serves as a protected amine intermediate for synthesizing cardiovascular agents, as described in medicinal chemistry literature focusing on beta-blockers. Its amino group enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic research has explored its potential in asymmetric catalysis for enantioselective synthesis, as reported in organic chemistry journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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