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(1H-pyrazolo[4,3-b]pyridin-6-yl)methanol
$200.00
CAS No.: 1934501-30-0
Catalog No.: 192903
Purity: 95%
MF: C7H7N3O
MW: 149.153
Storage: 2-8 degree Celsius
SMILES: N1N=CC2=NC=C(C=C21)CO
Catalog No.: 192903
Purity: 95%
MF: C7H7N3O
MW: 149.153
Storage: 2-8 degree Celsius
SMILES: N1N=CC2=NC=C(C=C21)CO
(1H-pyrazolo[4,3-b]pyridin-6-yl)methanol; CAS No.: 1934501-30-0; (1H-pyrazolo[4,3-b]pyridin-6-yl)methanol. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C8H7N3O and a molecular weight of 157.16 g/mol. It demonstrates a melting point in the range of 168-172 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as (1H-pyrazolo[4,3-b]pyridin-6-yl)methanol may cause skin irritation. The hydroxyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (1H-pyrazolo[4,3-b]pyridin-6-yl)methanol serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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