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6-bromo-5-methylpyrazolo[1,5-a]pyridine
$300.00
CAS No.: 1345121-23-4
Catalog No.: 192894
Purity: 95%
MF: C8H7BrN2
MW: 211.062
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=CC=2N(C1)N=CC2)C
Catalog No.: 192894
Purity: 95%
MF: C8H7BrN2
MW: 211.062
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=CC=2N(C1)N=CC2)C
6-bromo-5-methylpyrazolo[1,5-a]pyridine; CAS No.: 1345121-23-4; 6-bromo-5-methylpyrazolo[1,5-a]pyridine. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C9H6BrN2 and a molecular weight of 226.06 g/mol. It exhibits a melting point in the range of 142-146 C and demonstrates moderate solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 6-bromo-5-methylpyrazolo[1,5-a]pyridine may cause skin irritation. The bromo group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 6-bromo-5-methylpyrazolo[1,5-a]pyridine serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its bromo substituent enables participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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