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4-bromo-5-methylpyrazolo[1,5-a]pyridine
$375.00
CAS No.: 1345121-29-0
Catalog No.: 192895
Purity: 95%
MF: C8H7BrN2
MW: 211.062
Storage: 2-8 degree Celsius
SMILES: BrC=1C=2N(C=CC1C)N=CC2
Catalog No.: 192895
Purity: 95%
MF: C8H7BrN2
MW: 211.062
Storage: 2-8 degree Celsius
SMILES: BrC=1C=2N(C=CC1C)N=CC2
4-bromo-5-methylpyrazolo[1,5-a]pyridine; CAS No.: 1345121-29-0; 4-bromo-5-methylpyrazolo[1,5-a]pyridine. PROPERTIES: This compound presents as a white crystalline powder with molecular formula C9H6BrN2 and a molecular weight of 226.06 g/mol. It demonstrates a melting point in the range of 138-142 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 4-bromo-5-methylpyrazolo[1,5-a]pyridine may release toxic fumes upon heating. The bromo group requires careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical industry, 4-bromo-5-methylpyrazolo[1,5-a]pyridine serves as an intermediate for synthesizing anticancer agents, as described in medicinal chemistry literature focusing on kinase inhibitors. Its bromo substituent enables participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through nucleophilic aromatic substitution reactions. Academic research has explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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