The store will not work correctly when cookies are disabled.
We use cookies for optimal website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.
Allow cookies Deny
4-chloro-2-(trifluoromethyl)pyrazolo[1,5-a]pyrazine; CAS No.: 877402-79-4; 4-chloro-2-(trifluoromethyl)pyrazolo[1,5-a]pyrazine. PROPERTIES: 4-Chloro-2-(trifluoromethyl)pyrazolo[1,5-a]pyrazine presents as a dark crystalline solid with a characteristic halogenated odor. The compound exhibits strong electron-deficient character due to chloro and trifluoromethyl substituents and shows solubility in polar aprotic solvents. It is sensitive to light undergoing slow photooxidation. Recommended storage involves vacuum desiccators with appropriate drying agents and maintaining temperatures below 15 C. Safety data indicates potential for causing skin sensitization necessitating patch testing for prolonged exposure as per REACH regulations. APPLICATIONS: 4-Chloro-2-(trifluoromethyl)pyrazolo[1,5-a]pyrazine functions as an intermediate in the synthesis of dual PI3K/mTOR inhibitors documented in cancer research journals. Its chloro and trifluoromethyl substituents enable radiolabeling applications in medical imaging tracers as described in nuclear medicine communications. Furthermore, the compound contributes to synthesis of fluorescent dyes for biomolecular labeling described in photochemistry innovations.