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2-(Trifluoromethyl)pyrazolo[1,5-a]pyrazin-4-ol; CAS No.: 877402-82-9; 2-(trifluoromethyl)pyrazolo[1,5-a]pyrazin-4-ol. PROPERTIES: 2-(Trifluoromethyl)pyrazolo[1,5-a]pyrazin-4-ol exists as a white to pale yellow powder with a characteristic alcoholic odor. The compound demonstrates moderate polarity with a logP approximately 2.1 and shows good solubility in basic aqueous solutions. It exhibits typical alcohol reactivity undergoing oxidation to ketone. Recommended storage involves maintaining in tightly sealed containers at room temperature. Safety protocols recommend avoiding dust inhalation and providing local exhaust ventilation as per ACGIH threshold limit values for alcohols. APPLICATIONS: 2-(Trifluoromethyl)pyrazolo[1,5-a]pyrazin-4-ol serves as an intermediate in the preparation of SGLT2 inhibitors documented in diabetes research publications. Its hydroxyl and trifluoromethyl functionality enables formation of bioactive ethers and esters explored in medicinal chemistry. Furthermore, the compound contributes to synthesis of fluorescent probes for enzyme activity assays described in bioanalytical chemistry innovations.