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2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one
$250.00
CAS No.: 1255784-04-3
Catalog No.: 192568
Purity: 95%
MF: C12H9N3O
MW: 211.224
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=NN2C(C(NC=C2)=O)=C1
Catalog No.: 192568
Purity: 95%
MF: C12H9N3O
MW: 211.224
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=NN2C(C(NC=C2)=O)=C1
2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one; CAS No.: 1255784-04-3; 2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one. PROPERTIES: 2-Phenylpyrazolo[1,5-a]pyrazin-4(5H)-one exists as a pale yellow crystalline powder with a characteristic pyrazine odor. The compound demonstrates moderate electron-deficient character due to the fused heterocyclic system and shows solubility in DMF and DMSO. It exhibits typical ketone reactivity with nucleophiles. Recommended storage involves maintaining in tightly sealed containers at room temperature. Safety protocols recommend avoiding dust inhalation and providing local exhaust ventilation as per ACGIH threshold limit values for heterocyclic compounds. APPLICATIONS: 2-Phenylpyrazolo[1,5-a]pyrazin-4(5H)-one serves as an intermediate in the preparation of JAK kinase inhibitors documented in oncology research. Its pyrazolopyrazine framework enables formation of metal coordination complexes useful in homogeneous catalysis as reported in organometallic chemistry journals. Furthermore, the compound contributes to synthesis of fluorescent probes for biomolecular imaging described in photochemistry communications.
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