N2-methylpyrazine-2,3-diamine
$200.00
CAS No.: 84996-40-7
Catalog No.: 196342
Purity: 95%
MF: C5H8N4
MW: 124.147
Storage: 2-8 degree Celsius
SMILES: CNC1=NC=CN=C1N
Catalog No.: 196342
Purity: 95%
MF: C5H8N4
MW: 124.147
Storage: 2-8 degree Celsius
SMILES: CNC1=NC=CN=C1N
N2-methylpyrazine-2,3-diamine; CAS No.: 84996-40-7; N2-methylpyrazine-2,3-diamine. PROPERTIES: This compound presents an N2-methylpyrazine-2,3-diamine structure, combining a methylamino substituent and another amino group on the pyrazine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 134.1 g/mol (C5H7N5). The melting point ranges between 150-155 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: N2-Methylpyrazine-2,3-diamine serves as a specialized intermediate in pharmaceutical research. Its N2-methylpyrazine-2,3-diamine structure enables diverse reactivity patterns, including nucleophilic substitution at the pyrazine ring and hydrogen bonding interactions through the amino groups. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The methylamino group provides steric and electronic effects that influence binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the N2-methylpyrazine-2,3-diamine scaffold for improved biological activity and target engagement.
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